Water → HCID 54296428, compound

Participants

Reaction Steps

Ethyl (2-methylene-3,4-(dimethylmethylenedioxy)-5-(tert-butyldiphenylsilyloxy)cyclohexylidene)acetate (0.506 g) was dissolved in 10 ml of ethanol, and a catalytic amount of p-toluenesulfonic acid was added, followed by stirring the mixture at room temperature for 5 hours. Water was added to the reaction mixture, and extraction was conducted with diethyl ether. The extract was washed with a saturated sodium chloride aqueous solution, dried over anhydrous magnesium sulfate, and concentrated under reduced pressure. The obtained residue was purified by silica gel column chromatography to give 0.405 g of ethyl (2-methylene-3,4-dihydroxy-5-(tert-butyldiphenylsilyloxy)cyclohexylidene)acetate having the following property.

Provenance & Evidence