Pyridine → HCID 14204773, compound

Participants

Reaction Conditions

Reaction Steps

To 40 ml of acetonitrile were added 1.655 g (20.923 mmol) of pyridine and 1,961 g (20.406 mmol) of methanesulfonic acid (i.e., the amount of pyridine was 1,025 times that of methanesulfonic acid in a molar ratio), and the mixture was cooled to -20° C. A mixed gas of fluorine and nitrogen in a volumetric ratio of 1:4 was then introduced to the mixture at a rate of 50 ml/min under stirring. The amount of fluorine gas introduced was 40.0 mmol. After completion of the reaction, the solvent was distilled off, and 3,691 g ¢19.103 mmol) N-fluoropyridinium methanesulfonate was obtained by crystallizing with ether. The yield was

Provenance & Evidence