反应详情

In 1 ml of dimethylformamide was dissolved N-(13-benzyloxycarbonyltridecanoyloxy)sulfosuccinimide sodium salt (50 mg, 0.11 mmole). To the obtained solution, was added 5 mg of 10% palladium carbon and the mixture was stirred for 20 hours under an atmosphere of hydrogen. The reaction mixture was filtered and to the filtrate 30 ml of ethyl acetate was added. The mixture was stirred for 30 minutes and the solid that formed was collected by filtration and dried under reduced pressure to give N-(13-carboxytridecanoyloxy)sulfosuccinimide sodium salt (22 mg, 63%) having the following properties.

1. filtrationThe reaction mixture was filtered and to the filtrate 30 ml of ethyl acetate
2. additionwas added
3. stirringThe mixture was stirred for 30 minutes
4. customthe solid that formed
5. filtrationwas collected by filtration
6. customdried under reduced pressure