N-(13-benzyloxycarbonyltridecanoyloxy)sulfosuccinimide sodium salt → HCID 86748066, Verbindung

HRID 1742087Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1742087
[Na:1].C([O:9][C:10]([CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][C:24]([O:26][N:27]1[C:31](=[O:32])[CH2:30][CH:29]([S:33]([OH:36])(=[O:35])=[O:34])[C:28]1=[O:37])=[O:25])=[O:11])C1C=CC=CC=1>CN(C)C=O.[C].[Pd]>[Na:1].[C:10]([CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][C:24]([O:26][N:27]1[C:31](=[O:32])[CH2:30][CH:29]([S:33]([OH:36])(=[O:35])=[O:34])[C:28]1=[O:37])=[O:25])([OH:11])=[O:9]

Komponenten

4

Edukt 1

HCID 86748065N-(13-benzyloxycarbonyltridecanoyloxy)sulfosuccinimide sodium salt

Produkt 1

HCID 86748066HCID 86748066, VerbindungAusbeute 63 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 178418390HCID 178418390, VerbindungKatalysatorHCID 6228DimethylformamideLösungsmittel

Versuchsvorschrift

In 1 ml of dimethylformamide was dissolved N-(13-benzyloxycarbonyltridecanoyloxy)sulfosuccinimide sodium salt (50 mg, 0.11 mmole). To the obtained solution, was added 5 mg of 10% palladium carbon and the mixture was stirred for 20 hours under an atmosphere of hydrogen. The reaction mixture was filtered and to the filtrate 30 ml of ethyl acetate was added. The mixture was stirred for 30 minutes and the solid that formed was collected by filtration and dried under reduced pressure to give N-(13-carboxytridecanoyloxy)sulfosuccinimide sodium salt (22 mg, 63%) having the following properties.

Aufarbeitung

  1. filtrationThe reaction mixture was filtered and to the filtrate 30 ml of ethyl acetate
  2. additionwas added
  3. stirringThe mixture was stirred for 30 minutes
  4. customthe solid that formed
  5. filtrationwas collected by filtration
  6. customdried under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-31bed31fcabd4e19891a1e87e44d3ccb
Quelldatensatz
uspto-grants-1994_08
Patentnummer
US05336782

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