Hydrochloric Acid → HCID 19008804, compound

Participants

Reaction Conditions

Reaction Steps

A solution of 2-bromoethyl-3-methoxy benzothiophene-2-carboxamide (1.05 g) and 2-norbornylamine(0.42 g) in dry dimethyl formamide containing triethylamine (0.38 g) was heated under a nitrogen atmosphere at 80° C. for 8 hours. The solution was poured into water and extracted with ethyl acetate (3×50 ml), organic extracts washed with water (3×100 ml), dried and the solvent removed to give an oil which was converted to its hydrochloride to give N-[2-(2-norbornylamino) ethyl ]-3 -methoxy benzothiophene-2-carboxamide.

Provenance & Evidence