2-Chloro-4-fluoro-5-sulfamoylbenzoic acid → N-((1-(2-chloro-4-fluoro-5-sulfamoylbenzoyl)-4-phenylpiperidin-4-yl)methyl)-3-fluoro-4-(2-(4-methylpyridin-2-ylamino)thiazol-5-ylthio)picolinamide
Reaction equation
[Cl:38][c:39]1[c:40]([C:41](=[O:42])[OH:43])[cH:44][c:45]([S:49]([NH2:50])(=[O:51])=[O:52])[c:46]([F:48])[cH:47]1.[F:1][c:2]1[c:3]([C:22](=[O:23])[NH:24][CH2:25][C:26]2([c:32]3[cH:33][cH:34][cH:35][cH:36][cH:37]3)[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]2)[n:4][cH:5][cH:6][c:7]1[S:8][c:9]1[cH:10][n:11][c:12]([NH:14][c:15]2[n:16][cH:17][cH:18][c:19]([CH3:21])[cH:20]2)[s:13]1>>[F:1][c:2]1[c:3]([C:22](=[O:23])[NH:24][CH2:25][C:26]2([c:32]3[cH:33][cH:34][cH:35][cH:36][cH:37]3)[CH2:27][CH2:28][N:29]([C:41]([c:40]3[c:39]([Cl:38])[cH:47][c:46]([F:48])[c:45]([S:49]([NH2:50])(=[O:51])=[O:52])[cH:44]3)=[O:42])[CH2:30][CH2:31]2)[n:4][cH:5][cH:6][c:7]1[S:8][c:9]1[cH:10][n:11][c:12]([NH:14][c:15]2[n:16][cH:17][cH:18][c:19]([CH3:21])[cH:20]2)[s:13]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-8bed0600be234aca904229a72ab74933
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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