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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 174229Generated: October 26, 2026

Pyridine → 4-Hydroxy4-[3-(trifluoromethyl)phenyl]piperidine-1-carbonyl chloride

https://huagongshe.com/reaction/174229

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyridineHCID 1049—
ReactantTetrahydrofuranHCID 8028—
Reactant4-[3-(Trifluoromethyl)phenyl]-4-piperidinolHCID 75255—
ReactantTriphosgeneHCID 94429—
Product4-Hydroxy4-[3-(trifluoromethyl)phenyl]piperidine-1-carbonyl chlorideHCID 59011934—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-20242f4987b24a71a09f6dc5537a7ea7
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)