HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Dithionite → 5,6-Diamino-1,3-dicyclopropyluracil
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Dithionite | HCID 24489 | — |
| Reactant | 6-Amino-1,3-bis(cyclopropylmethyl)uracil | HCID 18624515 | — |
| Reactant | 6-Amino-1,3-dicyclopropyl-5-nitrosouracil | HCID 19005884 | — |
| Reactant | Sodium Nitrite | HCID 23668193 | — |
| Product | 5,6-Diamino-1,3-dicyclopropyluracil | HCID 19005888 | 84.9% |
Reaction Steps
The procedure similar to that described in Reference Example 1 was repeated except that 1.55 g (6.57 mmol) of Compound g prepared above and 2.86 g (16.4 mmol) of sodium hydrosulfite were employed in place of 6-amino-1,3-bis(cyclopropylmethyl)uracil and sodium nitrite, respectively. As a result, 1.24 g (yield: 75%) of Compound d was obtained as white powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05342841 |
| Source dataset | uspto-grants-1994_08 |
| ORD ID | ord-7f19b1ecd37541a5b447b5dec28647c5 |
| Source note | uspto-grants-1994_08 |