Acetone → HCID 19006193, compound

Participants

Reaction Steps

A mixture of 3-hydroxy-2-iodopyridine (22.1 g, 0.1M) and 4-dodecylbenzyl bromide (37.2 g, 0.101M) was stirred in sulpholane (100 ml) at 90° C. for 8 hours. Acetone was added and the precipitated product filtered and washed with acetone to yield a white solid (45 g). The product was recrystallised from a mixture of methanol and water, collected and dried at 60° C. (35 g).

Provenance & Evidence