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HRID1742943

反应详情

EQUATION

反应方程式

HRID 1742943 的结构方程式

REACTANTS

反应物

2
结构：Nc1c(F)c(F)c(F)c2c1c(=O)c(C(=O)O)cn2C1CC1
HCID13910947

5-Amino-1-cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

C13H9F3N2O3

结构：N[C@@H]1CNC[C@@H]1n1ccnn1
HCID70283180

未命名化合物

PRODUCTS

生成物

1
结构：Nc1c(F)c(N2C[C@@H](N)[C@@H](n3ccnn3)C2)c(F)c2c1c(=O)c(C(=O)O)cn2C1CC1
HCID70283680

未命名化合物

收率 65%

PROCEDURE

实验过程

Prepared by following the same procedure as described for Example 17 by using 5-amino-1-cyclopropyl -6,7,8-trifluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid and cis-3-amino-4-(1,2,3-triazol-1-yl)pyrrolidine. Yield: 65%, m.p. 275°-277° C. 1H NMR (TFA) δ: 1.33-1.50 (m, 4H), 4.32-5.12 (m, 6H), 6.34 (m, 1H), 8.64 (s, 1H), 8.89 (s, 1H), 9.16 (s, 1H).

WORKUP

后处理

  1. customPrepared