HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Amino-1-(2,4-difluorophenyl)-6,7,8-trifluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid → HCID 70282582, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Amino-1-(2,4-difluorophenyl)-6,7,8-trifluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid | HCID 14896552 | — |
| Reactant | rac-(3R,4S)-4-(1H-1,2,3-triazol-1-yl)pyrrolidin-3-amine | HCID 70283180 | — |
| Product | HCID 70282582 | HCID 70282582 | 66% |
Reaction Steps
Prepared by following the same procedure as described for Example 17 by using 5-amino-1-(2,4-difluorophenyl) -6,7,8-trifluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid and cis-3-amino-4-(1,2,3-triazol-1-yl)-pyrrolidine. Yield: 66%, m.p. 279°-281° C. 1H NMR (TFA) δ: 4.48-4.82 (m, 4H), 5.02 (m, 1H), 6.26 (m, 1H), 7.17 (m, 2H), 7.62 (m, 1H), 8.6 (s, 1H), 8.82 (d, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05342846 |
| Source dataset | uspto-grants-1994_08 |
| ORD ID | ord-393c0f69511f40e598d98e965662b115 |
| Source note | uspto-grants-1994_08 |