Thionyl Chloride → 3-[(2-Chlorophenyl)methyl]-1,2lambda~4~,3-oxathiazolidin-2-one

HRID 1743024Notes

Reaction equation

[OH:1][CH2:2][CH2:3][NH:4][CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[Cl:12].[S:13](Cl)(Cl)=[O:14]>>[Cl:12][C:7]1[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=1[CH2:5][N:4]1[CH2:3][CH2:2][O:1][S:13]1=[O:14]

Participants

Reactant 2

HCID 24386Thionyl Chloride

HCID 35615492-(2-Chloro-benzylamino)-ethanol

Product 1

HCID 152277033-[(2-Chlorophenyl)methyl]-1,2lambda~4~,3-oxathiazolidin-2-one

Procedure

contacting N-hydroxyethyl-2-chlorobenzylamine with thionyl chloride and an organic base to give N-(2-chlorobenzyl)-2-oxo-1,2,3-oxathiazolidine, and

Sources & evidence

ORD record: ord-096ee40e3a834535a4a6a2ce09495145
Source dataset: uspto-grants-1994_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05342953

Reaction notes

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