Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | 1-Iodo-2-methoxyethane | HCID 79136 | — |
| Reactant | HCID 9819936 | HCID 9819936 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 19006244 | HCID 19006244 | 79.8% |
Reaction Steps
To a suspension of 1-(4-pyridyl)-2,3-bis(hydroxy-methyl)-6,7-diethoxynaphthalene (7.0 g) in dry dimethylformamide (14 ml) is added 2-methoxyethyl iodide (7.35 g), and the mixture is stirred at 80° C. overnight. The mixture is allowed to cool, and thereto added ethyl acetate. The precipitated crystal is collected by filtration to give 4-[2,3-bis(hydroxymethyl)-6,7-diethoxy-1naphthyl]-N-(2-methoxyethyl)pyridinium iodide (8.50 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05342941 |
|---|
| Source dataset | uspto-grants-1994_08 |
|---|
| ORD ID | ord-76deec7c5bf648b1a23cc9216fd7f0ce |
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| Source note | uspto-grants-1994_08 |
|---|
