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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1743042Generated: October 31, 2026

2-Nitroimidazole → (S)-(+)-alpha-(chloromethyl)-2-nitro-1H-imidazole-1-ethanol

https://huagongshe.com/reaction/1743042

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-NitroimidazoleHCID 10701—
ReactantPotassium CarbonateHCID 11430—
Reactant(+)-EpichlorohydrinHCID 149428—
Product(S)-(+)-alpha-(chloromethyl)-2-nitro-1H-imidazole-1-ethanolHCID 11052772—

Reaction Steps

Alternatively, reaction of 2-nitroimidazole, anhydrous potassium carbonate, and (S)-(+)-epichlorohydrin as described in Example 1(a) gives the product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05342959
Source datasetuspto-grants-1994_08
ORD IDord-1006c8961de040a4a6d58575ce4c6cf1
Source noteuspto-grants-1994_08