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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1743044Generated: October 26, 2026

Aziridine → (R)-(-)-alpha-(1-Aziridinylmethyl)-2-nitro-1H-imidazole-1-ethanol

https://huagongshe.com/reaction/1743044

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAziridineHCID 9033—
Reactant(S)-(-)-2-Nitro-1-(2-oxiranylmethyl)-1H-imidazoleHCID 11768967—
SolventChloroformHCID 6212—
Product(R)-(-)-alpha-(1-Aziridinylmethyl)-2-nitro-1H-imidazole-1-ethanolHCID 10242276—

Reaction Steps

Reaction of (S)-(-)-2-nitro-1-(2-oxiranylmethyl)-1H-imidazole with 1H--aziridine as described in Example 1(e) gives the product, mp 119.5°-121° C. [α]D24 =-28.7° [c1.15, chloroform].

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05342959
Source datasetuspto-grants-1994_08
ORD IDord-9e55db9c9f4745fbb9a234bf0c106227
Source noteuspto-grants-1994_08