HCID 57018228, compound → HCID 57241412, compound

Participants

Reaction Steps

The residue was divided into three portions, and each portion was purified by a medium pressure silica gel column chromatography (Lobar size B, ethyl acetate-hexane 7:5→2:1). There were obtained a carbapenam ((6R,8R)-isomer, pale yellowish viscous liquid, 319 mg, 9.4%) derived from Compound 8a, and a mixture (76:24, pale yellowish viscous liquid, 2.06 g (containing about 5% of impurities), yield 58%. Yield of Compound S10 from Compound 8b was 75%) of Compound S10 and a carbapenam ((6S,8S)-isomer) derived from Compound 8c.

Provenance & Evidence