HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3-Dichloroaniline → 3-(2,3-Dichloroanilino)-4-(2-hydroxyanilino)-cyclobut-3-ene-1,2-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3-Dichloroaniline | HCID 11844 | — |
| Reactant | 3-Ethoxy-4-(2-hydroxyanilino)cyclobut-3-ene-1,2-dione | HCID 2826618 | — |
| Catalyst | Dimethyl Sulfoxide | HCID 679 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 3-(2,3-Dichloroanilino)-4-(2-hydroxyanilino)-cyclobut-3-ene-1,2-dione | HCID 9924473 | — |
Reaction Conditions
| Temperature | 110 °C |
|---|
Reaction Steps
To a solution of 3-ethoxy-4-(2-hydroxyanilino)-cyclobut-3-ene-1,2-dione (100 mg, 0.43 mmol) in toluene (2 mL) and DMSO (1 drop) was added 2,3-dichloroaniline (0.07 mL, 0.43 mmol) and reaction was stirred at 110° C. overnight. The resulting solid was collected by filtration, washed with ethyl acetate to remove toluene and dried in vacuo. LC-MS (m/z) 349 (M+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07008962B2 |
| Source dataset | uspto-grants-2006_03 |
| ORD ID | ord-e9617ac0878e431ca77d660b77514c97 |
| Source note | uspto-grants-2006_03 |