HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1743145Generated: November 2, 2026
4-Bromo-2-methylaniline → HCID 10270649, compound
https://huagongshe.com/reaction/1743145
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Bromo-2-methylaniline | HCID 11423 | — |
| Reactant | 3-Ethoxy-4-(2-hydroxyanilino)cyclobut-3-ene-1,2-dione | HCID 2826618 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 10270649 | HCID 10270649 | — |
Reaction Steps
To a solution of 3-ethoxy-4-(2-hydroxyanilino)-cyclobut-3-ene-1,2-dione (50 mg, 0.21 mmol) in DMSO (1.5 mL) was added 4-bromo-2-methylaniline (40 mg, 0.21 mmol) and reaction was stirred at 110° C. overnight. Reaction was purified on HPLC (acetonitrile:water) and product was concentrated down. Solid was dried in vacuo. LC-MS (m/z) 373 (M+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07008962B2 |
|---|
| Source dataset | uspto-grants-2006_03 |
|---|
| ORD ID | ord-81a142c583f149d39cfb04ca356ede44 |
|---|
| Source note | uspto-grants-2006_03 |
|---|
