4-Methyloxybenzyl chloride → HCID 10300637, compound

HRID 1743212Notes

Reaction equation

HRID 1743212 reaction equation
[CH3:1][C:2]1([CH3:28])[CH:6]([C:7]2[CH:12]=[CH:11][C:10]([N:13]3[CH2:18][CH2:17][N:16]([CH3:19])[CH2:15][CH2:14]3)=[CH:9][CH:8]=2)[C:5]2[C:20]([CH3:27])=[C:21]([OH:26])[C:22]([CH3:25])=[C:23]([CH3:24])[C:4]=2[O:3]1.[CH3:29][O:30][C:31]1[CH:38]=[CH:37][C:34]([CH2:35]Cl)=[CH:33][CH:32]=1>>[CH3:29][O:30][C:31]1[CH:38]=[CH:37][C:34]([CH2:35][O:26][C:21]2[C:22]([CH3:25])=[C:23]([CH3:24])[C:4]3[O:3][C:2]([CH3:28])([CH3:1])[CH:6]([C:7]4[CH:8]=[CH:9][C:10]([N:13]5[CH2:18][CH2:17][N:16]([CH3:19])[CH2:15][CH2:14]5)=[CH:11][CH:12]=4)[C:5]=3[C:20]=2[CH3:27])=[CH:33][CH:32]=1

Participants

3

Reactant 2

HCID 699934-Methyloxybenzyl chlorideHCID 22238256HCID 22238256, compound

Product 1

HCID 10300637HCID 10300637, compoundYield 42%

Procedure

Using 2,2,4,6,7-pentamethyl-3-[4-(4-methyl-1-piperazinyl)phenyl]-2,3-dihydrobenzofuran-5-ol and 4-methoxybenzyl chloride, the title compound was obtained in the same manner as In Example 1.

Sources & evidence

ORD record
ord-c94d9b72c02a41bb9a73fa2eeba0985e
Source dataset
uspto-grants-2006_03
Patent number
US07008950B1

Reaction notes

Loading…