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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1743221Generated: November 2, 2026

3-(Chloromethyl)pyridine hydrochloride → 3-(4-Isopropylphenyl)-2,2,4,6,7-pentamethyl-5-(3-pyridylmethyloxy)-2,3-dihydrobenzofuran

https://huagongshe.com/reaction/1743221

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Chloromethyl)pyridine hydrochlorideHCID 23394—
Reactant3-(4-Isopropylphenyl)-2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-olHCID 10881888—
Product3-(4-Isopropylphenyl)-2,2,4,6,7-pentamethyl-5-(3-pyridylmethyloxy)-2,3-dihydrobenzofuranHCID 1011255476%

Reaction Steps

Using 3-(4-isopropylphenyl)-2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-ol and 3-chloromethylpyridine hydrochloride, the title compound was obtained in the same manner as in Example 1. This was oily.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07008950B1
Source datasetuspto-grants-2006_03
ORD IDord-b24d8f83163c41e5897e63b675318bf1
Source noteuspto-grants-2006_03