HCID 21587862, compound → HCID 91584956, compound

HRID 1743243Notes

Reaction equation

HRID 1743243 reaction equation
[C:1]([C@@H:4]1[CH2:8][S:7][C@H:6]2[CH2:9][C@@H:10]([NH:13][C:14](=[O:20])[O:15][C:16]([CH3:19])([CH3:18])[CH3:17])[C:11](=[O:12])[N:5]12)(=[O:3])[NH2:2].C(OC(N[C@H]1C(=O)N2[C@H](SC[C@H]2C(OC)=O)C1)=O)(C)(C)C>>[C:1]([C@@H:4]1[CH2:8][S:7][C@@H:6]2[CH2:9][C@@H:10]([NH:13][C:14](=[O:20])[O:15][C:16]([CH3:18])([CH3:17])[CH3:19])[C:11](=[O:12])[N:5]12)(=[O:3])[NH2:2]

Participants

3

Reactant 2

HCID 21587862HCID 21587862, compoundHCID 90686806HCID 90686806, compound

Product 1

HCID 91584956HCID 91584956, compound

Procedure

was obtained in analogy to the synthesis of 2e) starting from 540 mg of methyl (3R,6R,8R)-6-tert-butoxycarbonylamino-5-oxohexahydropyrrolo[2,1-b]thiazole-3-carboxylate (2d).

Sources & evidence

ORD record
ord-37088a53ac084e1cbba6fa1a59c8caad
Source dataset
uspto-grants-2006_03
Patent number
US07008957B2

Reaction notes

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