HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 2-Propenoic acid, 3-phenyl-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | (R)-2-Bromo-3-phenylpropionic acid | HCID 11746403 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 2-Propenoic acid, 3-phenyl- | HCID 8784 | — |
Reaction Steps
5 g of crude (2R)-2-bromo-3-phenylpropionic acid (HPLC: 92.5%) were dissolved in 20 ml of ethyl acetate and treated at room temperature with 2.7 ml of triethylamine. After a stirring time of about 150 minutes, no precipitation of the product was to be observed. An HPLC analysis of the solution showed that the (2R)-2-bromo-3-phenyl-propionic acid had reacted completely to give cinnamic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07009047B2 |
| Source dataset | uspto-grants-2006_03 |
| ORD ID | ord-fa8f039f982e47f59386fc1d90ea5567 |
| Source note | uspto-grants-2006_03 |