Cyclohexylamine → HCID 10335732, compound

HRID 1743293Notes

Reaction equation

HRID 1743293 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[N:8][C:9]2[C:14]([C:15]=1Cl)=[CH:13][CH:12]=[CH:11][C:10]=2[N+:17]([O-])=O)=[O:5])[CH3:2].[CH:20]1([NH2:26])[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21]1>>[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[N:8][C:9]2[C:14]([C:15]=1[NH:26][CH:20]1[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21]1)=[CH:13][CH:12]=[CH:11][C:10]=2[NH2:17])=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 7965CyclohexylamineHCID 11196760Ethyl 4-chloro-8-nitroquinoline-3-carboxylate

Product 1

HCID 10335732HCID 10335732, compoundYield 88%

Procedure

The compound prepared in Example 3 was reacted with cyclohexylamine according to the method as described in Example 4 and the obtained compound was treated as described in Example 14 to prepare the title compound (yield 88%).

Workup

  1. additionthe obtained compound was treated

Sources & evidence

ORD record
ord-6b728577691e44e9ba8d82c98790f058
Source dataset
uspto-grants-2006_03
Patent number
US07009053B2

Reaction notes

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