1-Naphthalenemethanamine → HCID 10474377, compound

HRID 1743294Notes

Reaction equation

HRID 1743294 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[N:8][C:9]2[C:14]([C:15]=1Cl)=[CH:13][CH:12]=[CH:11][C:10]=2[N+:17]([O-])=O)=[O:5])[CH3:2].[C:20]1([CH2:30][NH2:31])[C:29]2[C:24](=[CH:25][CH:26]=[CH:27][CH:28]=2)[CH:23]=[CH:22][CH:21]=1>>[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[N:8][C:9]2[C:14]([C:15]=1[NH:31][CH2:30][C:20]1[C:29]3[C:24](=[CH:25][CH:26]=[CH:27][CH:28]=3)[CH:23]=[CH:22][CH:21]=1)=[CH:13][CH:12]=[CH:11][C:10]=2[NH2:17])=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 83551-NaphthalenemethanamineHCID 11196760Ethyl 4-chloro-8-nitroquinoline-3-carboxylate

Product 1

HCID 10474377HCID 10474377, compoundYield 80%

Procedure

The compound prepared in Example 3 was reacted with 1-naphthalenmethyl-amine according to the method as described in Example 4 and the obtained compound was treated as described in Example 14 to prepare the title compound (yield 80%).

Workup

  1. additionthe obtained compound was treated

Sources & evidence

ORD record
ord-ab9719c78ab04acc897d2bfb8522a393
Source dataset
uspto-grants-2006_03
Patent number
US07009053B2

Reaction notes

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