(2-Thienylmethyl)amine → HCID 10471664, compound

HRID 1743295Notes

Reaction equation

HRID 1743295 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[N:8][C:9]2[C:14]([C:15]=1Cl)=[CH:13][CH:12]=[CH:11][C:10]=2[N+:17]([O-])=O)=[O:5])[CH3:2].[S:20]1[CH:24]=[CH:23][CH:22]=[C:21]1[CH2:25][NH2:26]>>[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[N:8][C:9]2[C:14]([C:15]=1[NH:26][CH2:25][C:21]1[S:20][CH:24]=[CH:23][CH:22]=1)=[CH:13][CH:12]=[CH:11][C:10]=2[NH2:17])=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 34005(2-Thienylmethyl)amineHCID 11196760Ethyl 4-chloro-8-nitroquinoline-3-carboxylate

Product 1

HCID 10471664HCID 10471664, compoundYield 89%

Procedure

The compound prepared in Example 3 was reacted with thiophen-2-ylmethyl-amine according to the method as described in Example 4 and the obtained compound was treated as described in Example 14 to prepare the title compound (yield 89%).

Workup

  1. additionthe obtained compound was treated

Sources & evidence

ORD record
ord-a29609f3066b4a73853075f46403eab1
Source dataset
uspto-grants-2006_03
Patent number
US07009053B2

Reaction notes

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