Benzo-1,3-dioxole-5-methylamine → HCID 10428907, compound

HRID 1743297Notes

Reaction equation

HRID 1743297 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[N:8][C:9]2[C:14]([C:15]=1Cl)=[CH:13][CH:12]=[CH:11][C:10]=2[N+:17]([O-])=O)=[O:5])[CH3:2].[CH2:20]([NH2:30])[C:21]1[CH:29]=[CH:28][C:27]2[O:26][CH2:25][O:24][C:23]=2[CH:22]=1>>[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[N:8][C:9]2[C:14]([C:15]=1[NH:30][CH2:20][C:21]1[CH:29]=[CH:28][C:27]3[O:26][CH2:25][O:24][C:23]=3[CH:22]=1)=[CH:13][CH:12]=[CH:11][C:10]=2[NH2:17])=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 75799Benzo-1,3-dioxole-5-methylamineHCID 11196760Ethyl 4-chloro-8-nitroquinoline-3-carboxylate

Product 1

HCID 10428907HCID 10428907, compoundYield 91%

Procedure

The compound prepared in Example 3 was reacted with piperonylamine according to the method as described in Example 4 and the obtained compound was treated as described in Example 14 to prepare the title compound (yield 91%).

Workup

  1. additionthe obtained compound was treated

Sources & evidence

ORD record
ord-f2a09969faa8415085257e7f01f5cdf2
Source dataset
uspto-grants-2006_03
Patent number
US07009053B2

Reaction notes

Loading…