Isopropylamine → HCID 10468524, compound

HRID 1743302Notes

Reaction equation

HRID 1743302 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[N:8][C:9]2[C:14]([C:15]=1Cl)=[CH:13][CH:12]=[CH:11][C:10]=2[N+:17]([O-])=O)=[O:5])[CH3:2].[CH:20]([NH2:23])([CH3:22])[CH3:21]>>[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[N:8][C:9]2[C:14]([C:15]=1[NH:23][CH:20]([CH3:22])[CH3:21])=[CH:13][CH:12]=[CH:11][C:10]=2[NH2:17])=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 6363IsopropylamineHCID 11196760Ethyl 4-chloro-8-nitroquinoline-3-carboxylate

Product 1

HCID 10468524HCID 10468524, compoundYield 80%

Procedure

The compound prepared in Example 3 was reacted with isopropylamine according to the method as described in Example 4 and the obtained compound was treated as described in Example 14 to prepare the title compound (yield 80%).

Workup

  1. additionthe obtained compound was treated

Sources & evidence

ORD record
ord-1fb38f6351184ac295c1cdb0fb5fe284
Source dataset
uspto-grants-2006_03
Patent number
US07009053B2

Reaction notes

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