3-Fluorobenzylamine → HCID 9997314, compound

HRID 1743304Notes

Reaction equation

HRID 1743304 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[N:8][C:9]2[C:14]([C:15]=1Cl)=[CH:13][CH:12]=[CH:11][C:10]=2[N+:17]([O-])=O)=[O:5])[CH3:2].[F:20][C:21]1[CH:22]=[C:23]([CH:26]=[CH:27][CH:28]=1)[CH2:24][NH2:25]>>[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[N:8][C:9]2[C:14]([C:15]=1[NH:25][CH2:24][C:23]1[CH:26]=[CH:27][CH:28]=[C:21]([F:20])[CH:22]=1)=[CH:13][CH:12]=[CH:11][C:10]=2[NH2:17])=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 668533-FluorobenzylamineHCID 11196760Ethyl 4-chloro-8-nitroquinoline-3-carboxylate

Product 1

HCID 9997314HCID 9997314, compoundYield 90%

Procedure

The compound prepared in Example 3 was reacted with 3-fluoro-benzylamine according to the method as described in Example 4 and the obtained compound was treated as described in Example 14 to prepare the title compound (yield 90%).

Workup

  1. additionthe obtained compound was treated

Sources & evidence

ORD record
ord-c820137a770844f981fd5b964ffe0f0f
Source dataset
uspto-grants-2006_03
Patent number
US07009053B2

Reaction notes

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