3-Isopropoxypropylamine → HCID 10426835, compound

HRID 1743305Notes

Reaction equation

HRID 1743305 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[N:8][C:9]2[C:14]([C:15]=1Cl)=[CH:13][CH:12]=[CH:11][C:10]=2[N+:17]([O-])=O)=[O:5])[CH3:2].[CH:20]([O:23][CH2:24][CH2:25][CH2:26][NH2:27])([CH3:22])[CH3:21]>>[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[N:8][C:9]2[C:14]([C:15]=1[NH:27][CH2:26][CH2:25][CH2:24][O:23][CH:20]([CH3:22])[CH3:21])=[CH:13][CH:12]=[CH:11][C:10]=2[NH2:17])=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 761943-IsopropoxypropylamineHCID 11196760Ethyl 4-chloro-8-nitroquinoline-3-carboxylate

Product 1

HCID 10426835HCID 10426835, compoundYield 88%

Procedure

The compound prepared in Example 3 was reacted with 3-isopropoxy-propylamine according to the method as described in Example 4 and the obtained compound was treated as described in Example 14 to prepare the title compound (yield 88%).

Workup

  1. additionthe obtained compound was treated

Sources & evidence

ORD record
ord-a91de6faa1d34a46a7ecdc8109e5ada7
Source dataset
uspto-grants-2006_03
Patent number
US07009053B2

Reaction notes

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