2-Chlorobenzylamine → HCID 10066811, compound

HRID 1743313Notes

Reaction equation

HRID 1743313 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[N:8][C:9]2[C:14]([C:15]=1Cl)=[CH:13][CH:12]=[CH:11][C:10]=2[N+:17]([O-])=O)=[O:5])[CH3:2].[Cl:20][C:21]1[CH:28]=[CH:27][CH:26]=[CH:25][C:22]=1[CH2:23][NH2:24]>>[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[N:8][C:9]2[C:14]([C:15]=1[NH:24][CH2:23][C:22]1[CH:25]=[CH:26][CH:27]=[CH:28][C:21]=1[Cl:20])=[CH:13][CH:12]=[CH:11][C:10]=2[NH2:17])=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 666482-ChlorobenzylamineHCID 11196760Ethyl 4-chloro-8-nitroquinoline-3-carboxylate

Product 1

HCID 10066811HCID 10066811, compoundYield 83%

Procedure

The compound prepared in Example 3 was reacted with 2-chloro-benzylamine according to the method as described in Example 4 and the obtained compound was treated as described in Example 14 to prepare the title compound (yield 83%).

Workup

  1. additionthe obtained compound was treated

Sources & evidence

ORD record
ord-d70a038add94408085cd0074972081ae
Source dataset
uspto-grants-2006_03
Patent number
US07009053B2

Reaction notes

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