4-Chlorobenzylamine → HCID 10043796, compound

HRID 1743314Notes

Reaction equation

HRID 1743314 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[N:8][C:9]2[C:14]([C:15]=1Cl)=[CH:13][CH:12]=[CH:11][C:10]=2[N+:17]([O-])=O)=[O:5])[CH3:2].[Cl:20][C:21]1[CH:28]=[CH:27][C:24]([CH2:25][NH2:26])=[CH:23][CH:22]=1>>[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[N:8][C:9]2[C:14]([C:15]=1[NH:26][CH2:25][C:24]1[CH:27]=[CH:28][C:21]([Cl:20])=[CH:22][CH:23]=1)=[CH:13][CH:12]=[CH:11][C:10]=2[NH2:17])=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 660364-ChlorobenzylamineHCID 11196760Ethyl 4-chloro-8-nitroquinoline-3-carboxylate

Product 1

HCID 10043796HCID 10043796, compoundYield 85%

Procedure

The compound prepared in Example 3 was reacted with 4-chloro-benzylamine according to the method as described in Example 4 and the obtained compound was treated as described in Example 14 to prepare the title compound (yield 85%).

Workup

  1. additionthe obtained compound was treated

Sources & evidence

ORD record
ord-276066ccfc60477ca0b1db5dd71e9f60
Source dataset
uspto-grants-2006_03
Patent number
US07009053B2

Reaction notes

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