2,4-Dichlorobenzylamine → HCID 69527755, compound

HRID 1743315Notes

Reaction equation

HRID 1743315 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[N:8][C:9]2[C:14]([C:15]=1Cl)=[CH:13][CH:12]=[CH:11][C:10]=2[N+:17]([O-])=O)=[O:5])[CH3:2].[Cl:20][C:21]1[CH:28]=[C:27]([Cl:29])[CH:26]=[CH:25][C:22]=1[CH2:23][NH2:24]>>[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[N:8][C:9]2[C:14]([C:15]=1[NH:24][CH2:23][C:22]1[CH:25]=[CH:26][C:27]([Cl:29])=[CH:28][C:21]=1[Cl:20])=[CH:13][CH:12]=[CH:11][C:10]=2[NH2:17])=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 14852,4-DichlorobenzylamineHCID 11196760Ethyl 4-chloro-8-nitroquinoline-3-carboxylate

Product 1

HCID 69527755HCID 69527755, compoundYield 88%

Procedure

The compound prepared in Example 3 was reacted with 2,4-dichloro-benzylamine according to the method as described in Example 4 and the obtained compound was treated as described in Example 14 to prepare the title compound (yield 88%).

Workup

  1. additionthe obtained compound was treated

Sources & evidence

ORD record
ord-b261fda18c1e4b00b28d7e0c3da77a7f
Source dataset
uspto-grants-2006_03
Patent number
US07009053B2

Reaction notes

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