2,3-Dimethoxybenzylamine → HCID 69528328, compound

HRID 1743316Notes

Reaction equation

HRID 1743316 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[N:8][C:9]2[C:14]([C:15]=1Cl)=[CH:13][CH:12]=[CH:11][C:10]=2[N+:17]([O-])=O)=[O:5])[CH3:2].[CH3:20][O:21][C:22]1[C:29]([O:30][CH3:31])=[CH:28][CH:27]=[CH:26][C:23]=1[CH2:24][NH2:25]>>[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[N:8][C:9]2[C:14]([C:15]=1[NH:25][CH2:24][C:23]1[CH:26]=[CH:27][CH:28]=[C:29]([O:30][CH3:31])[C:22]=1[O:21][CH3:20])=[CH:13][CH:12]=[CH:11][C:10]=2[NH2:17])=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 781062,3-DimethoxybenzylamineHCID 11196760Ethyl 4-chloro-8-nitroquinoline-3-carboxylate

Product 1

HCID 69528328HCID 69528328, compoundYield 91%

Procedure

The compound prepared in Example 3 was reacted with 2,3-dimethoxy-benzylamine according to the method as described in Example 4 and the obtained compound was treated as described in Example 14 to prepare the title compound (yield 91%).

Workup

  1. additionthe obtained compound was treated

Sources & evidence

ORD record
ord-e44f83102c7a4066b2439e5ea7d15475
Source dataset
uspto-grants-2006_03
Patent number
US07009053B2

Reaction notes

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