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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1743318Generated: October 25, 2026

2-(2-Amino-ethyl)-phenylamine → 8-Amino-4-[2-(2-amino-phenyl)-ethylamino]-quinoline-3-carboxylic acid ethyl ester

https://huagongshe.com/reaction/1743318

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(2-Amino-ethyl)-phenylamineHCID 2750512—
ReactantEthyl 4-chloro-8-nitroquinoline-3-carboxylateHCID 11196760—
Product8-Amino-4-[2-(2-amino-phenyl)-ethylamino]-quinoline-3-carboxylic acid ethyl esterHCID 1006647491%

Reaction Steps

The compound prepared in Example 3 was reacted with 2-(2-amino-phenyl)-ethylamine according to the method as described in Example 4 and the obtained compound was treated as described in Example 14 to prepare the title compound (yield 91%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07009053B2
Source datasetuspto-grants-2006_03
ORD IDord-6f86e38d92c843668cde44b8a6eadb25
Source noteuspto-grants-2006_03