(3,5-Dimethoxyphenyl)methanamine → HCID 69527482, compound

HRID 1743319Notes

Reaction equation

HRID 1743319 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[N:8][C:9]2[C:14]([C:15]=1Cl)=[CH:13][CH:12]=[CH:11][C:10]=2[N+:17]([O-])=O)=[O:5])[CH3:2].[CH3:20][O:21][C:22]1[CH:23]=[C:24]([CH:27]=[C:28]([O:30][CH3:31])[CH:29]=1)[CH2:25][NH2:26]>>[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[N:8][C:9]2[C:14]([C:15]=1[NH:26][CH2:25][C:24]1[CH:27]=[C:28]([O:30][CH3:31])[CH:29]=[C:22]([O:21][CH3:20])[CH:23]=1)=[CH:13][CH:12]=[CH:11][C:10]=2[NH2:17])=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 420973(3,5-Dimethoxyphenyl)methanamineHCID 11196760Ethyl 4-chloro-8-nitroquinoline-3-carboxylate

Product 1

HCID 69527482HCID 69527482, compoundYield 87%

Procedure

The compound prepared in Example 3 was reacted with 3,5-dimethoxy-benzylamine according to the method as described in Example 4 and the obtained compound was treated as described in Example 14 to prepare the title compound (yield 87%).

Workup

  1. additionthe obtained compound was treated

Sources & evidence

ORD record
ord-bd4ea99e05de452cbfadfc3c17ad69b2
Source dataset
uspto-grants-2006_03
Patent number
US07009053B2

Reaction notes

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