HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Ethyl-2-(2-(4-nitrophenoxy)ethyl)pyridine → 4-[2-(5-Ethyl-2-pyridyl)ethoxy]aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Ethyl-2-(2-(4-nitrophenoxy)ethyl)pyridine | HCID 13314806 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-[2-(5-Ethyl-2-pyridyl)ethoxy]aniline | HCID 11499709 | — |
Reaction Steps
A solution of 4-(2-(5-ethyl-2-pyridyl)ethoxy)nitrobenzene (23 g) in methanol is hydrogenated under atmospheric pressure in the presence of 10% Pd on carbon (50% humid, 2.5 g). The catalyst is removed by filtering. Distilling the solvent off under reduced pressure gives 4-(2-(5-ethyl-2-pyridyl)ethoxy)aniline as crude oil (20 g, 98%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07009057B2 |
| Source dataset | uspto-grants-2006_03 |
| ORD ID | ord-9f91bea274924d44895df78dabcf5efc |
| Source note | uspto-grants-2006_03 |