Toluene → HCID 135433152, compound

Participants

Reaction Conditions

Reaction Steps

19.6 g (44.9 mmol) of (R)-N-(5-nitrosalicylidene)-2-amino-1,1-di(2-methoxyphenyl)-1-propanol, 8.96 g (44.9 mmol) of cupric acetate, and 160 g of toluene were mixed in a flask and reacted at 80° C. for 1 hr under stirring. 100 g of n-heptane were added to the reaction solution to precipitate blue-green chrystals. The precipitated reaction mixture was cooled to 10° C. and filtered to collect the crystals. Collected crystals were washed with 100 g of n-heptane, and dried at room temperature to give 22.1 g of a copper complex of (R) N-(5-nitro-salicylidene)-2amino-1,1-di(2-methoxyphenyl)-1-propanol in a yield of 99.0%.

Provenance & Evidence