(Diethylamino)sulfur trifluoride → HCID 22234980, compound

HRID 1743545Notes

Reaction equation

HRID 1743545 reaction equation
O[CH2:2][CH2:3][CH2:4][C:5]([CH2:10][C:11]1[CH:16]=[CH:15][C:14]([C:17]([F:20])([F:19])[F:18])=[CH:13][CH:12]=1)([C:8]#[N:9])[C:6]#[N:7].C(N(S(F)(F)[F:27])CC)C>ClCCl>[F:27][CH2:2][CH2:3][CH2:4][C:5]([CH2:10][C:11]1[CH:16]=[CH:15][C:14]([C:17]([F:20])([F:19])[F:18])=[CH:13][CH:12]=1)([C:8]#[N:9])[C:6]#[N:7]

Participants

4

Reactant 2

HCID 123472(Diethylamino)sulfur trifluorideHCID 22234986HCID 22234986, compound

Product 1

HCID 22234980HCID 22234980, compoundYield 5%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Using 0.80 g of 2-(3-hydroxypropyl)-2-(4-(trifluoromethyl)benzyl)-malononitrile, 8 ml of dichloromethane and 0.3 ml of Diethylaminosulfur trifluoride, and according to the process described in the Production Example 11, there was obtained 0.05 g of 2-(3-fluoropropyl)-2-(4-(trifluoromethyl)benzyl)malononitrile (the present compound (14)).

Sources & evidence

ORD record
ord-a96d257beb114659b84ece592bb1da3a
Source dataset
uspto-grants-2006_03
Patent number
US07011838B2

Reaction notes

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