HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 22235069, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 3-Bromo-1,1,1-trifluoropropane | HCID 2725114 | — |
| Reactant | HCID 22235013 | HCID 22235013 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 22235069 | HCID 22235069 | 21.3% |
Reaction Steps
Using 1.00 g of (3,4-difluorobenzyl)malononitrile, 10 ml of N,N-di-methylformamide, 0.20 g of sodium hydride (60% in oil), and 1.38 g of 1-bromo-3,3,3-trifluoropropane, and according to the process described in the Production Example 1, there was obtained 0.32 g of 2-(3,4-difluorobenzyl)-2-(3,3,3-trifluoropropyl)malononitrile (the present compound (19)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07011838B2 |
| Source dataset | uspto-grants-2006_03 |
| ORD ID | ord-3070e16856694e9c868aa32e2552dbe7 |
| Source note | uspto-grants-2006_03 |