HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cesium carbonate → 2-(4-Chlorobenzyl)-2-(2,2,3,3-tetrafluoropropyl)malononitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 2-((4-Chlorophenyl)methyl)propanedinitrile | HCID 18082 | — |
| Reactant | 2,2,3,3-Tetrafluoropropyl trifluoromethanesulfonate | HCID 3792475 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-(4-Chlorobenzyl)-2-(2,2,3,3-tetrafluoropropyl)malononitrile | HCID 22234996 | 7.5% |
Reaction Steps
Using 1.0 g of (4-chlorobenzyl)malononitrile, 15 ml of N,N-di-methylformamide, 0.073 g of cesium carbonate, and 1.47 g of 2,2,3,3-tetra-fluoropropyl trifluoromethanesulfonate, and according to the process described in the Production Example 1, there was obtained 0.12 g of 2-(4-chlorobenzyl)-2-(2,2,3,3-tetrafluoropropyl)malononitrile (the present compound (25)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07011838B2 |
| Source dataset | uspto-grants-2006_03 |
| ORD ID | ord-b81e9bafde684c4eb30043b5a835c62a |
| Source note | uspto-grants-2006_03 |