HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 22235028, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 3-Bromo-1,1,1-trifluoropropane | HCID 2725114 | — |
| Reactant | (4-(Trifluoromethoxy)benzyl)malononitrile | HCID 22235052 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 22235028 | HCID 22235028 | 21% |
Reaction Steps
Using 0.50 g of (4-(trifluoromethoxy)benzyl)malononitrile, 8 ml of N,N-dimethylformamide, 96 mg of sodium hydride (60% in oil), and 0.74 g of 1-bromo-3,3,3-trifluoropropane, and according to the process described in the Production Example 1, there was obtained 0.14 g of 2-(3,3,3-trifluoropropyl)-2-(4-(trifluoromethoxy)benzyl)malononitrile (the present compound (50)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07011838B2 |
| Source dataset | uspto-grants-2006_03 |
| ORD ID | ord-a453923cb9c14d4eb048e41ae4fa3239 |
| Source note | uspto-grants-2006_03 |