HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → 2-(2-Chloro-4-(trifluoromethyl)benzyl)-2-(3,4,4-trifluoro-3-butenyl)malononitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 1-(Bromomethyl)-2-chloro-4-(trifluoromethyl)benzene | HCID 22058559 | — |
| Reactant | (3,4,4-Trifluoro-3-butenyl)malononitrile | HCID 22185753 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-(2-Chloro-4-(trifluoromethyl)benzyl)-2-(3,4,4-trifluoro-3-butenyl)malononitrile | HCID 22235077 | 45% |
Reaction Steps
Using 0.30 g of (3,4,4-trifluoro-3-butenyl)malononitrile, 5 ml of N,N-dimethylformamide, 75 mg of sodium hydride (60% in oil), and 0.52 g of 2-chloro-4-(trifluoromethyl)benzylbromide, and according to the process described in the Production Example 1, there was obtained 0.28 g of 2-(2-chloro-4-(trifluoromethyl)benzyl)-2-(3,4,4-trifluoro-3-butenyl)malononitrile (the present compound (62)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07011838B2 |
| Source dataset | uspto-grants-2006_03 |
| ORD ID | ord-16a6650fc2774a35b38377754004f805 |
| Source note | uspto-grants-2006_03 |