HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Sodium hydride → 2-(3,3,3-Trifluoropropyl)-2-(4-(trifluoromethyl)benzyl)malononitrile
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Sodium hydride | HCID 24758 | — |
| Edukt | 3-Bromo-1,1,1-trifluoropropane | HCID 2725114 | — |
| Edukt | (4-(Trifluoromethyl)benzyl)malononitrile | HCID 10656743 | — |
| Lösungsmittel | Dimethylformamide | HCID 6228 | — |
| Produkt | 2-(3,3,3-Trifluoropropyl)-2-(4-(trifluoromethyl)benzyl)malononitrile | HCID 22235040 | 42% |
Reaktionsschritte
Using 0.50 g of (4-(trifluoromethyl)benzyl)malononitrile, 6 ml of N,N-dimethylformamide, 98 mg of sodium hydride (60% in oil), and 0.43 g of 1-bromo-3,3,3-trifluoropropane, and according to the process described in the Production Example 1, there was obtained 0.30 g of 2-(3,3,3-trifluoropropyl)-2-(4-(trifluoromethyl)benzyl)malononitrile (the present compound (74)).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07011838B2 |
| Quelldatensatz | uspto-grants-2006_03 |
| ORD ID | ord-59c5d395971a4723a030d6dfabf945d1 |
| Quellennotiz | uspto-grants-2006_03 |