Sodium borohydride → HCID 22235063, compound

HRID 1743633Notes

Reaction equation

HRID 1743633 reaction equation
[F:1][C:2]1[CH:13]=[C:12]([F:14])[CH:11]=[C:10]([F:15])[C:3]=1[CH:4]=[C:5]([C:8]#[N:9])[C:6]#[N:7].[BH4-].[Na+]>C(O)C>[F:1][C:2]1[CH:13]=[C:12]([F:14])[CH:11]=[C:10]([F:15])[C:3]=1[CH2:4][CH:5]([C:8]#[N:9])[C:6]#[N:7]

Participants

4

Reactant 2

HCID 4311764Sodium borohydrideHCID 22234971HCID 22234971, compound

Product 1

HCID 22235063HCID 22235063, compoundYield 90%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Using 1.42 g of (2,4,6-trifluorobenzyliden)malononitrile, 50 ml of ethanol and 0.08 g of sodium borohydride, and according to the process described in the REFERENCE PRODUCTION EXAMPLE 3, there was obtained 1.29 g of (2,4,6-trifluorobenzyl)malononitrile (the intermediate (21)).

Sources & evidence

ORD record
ord-6370f2df6de140b3b37a3f49cf66c512
Source dataset
uspto-grants-2006_03
Patent number
US07011838B2

Reaction notes

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