m-Chloroperbenzoic acid → 4-[2-(Oxiran-2-yl)ethoxy]benzonitrile

Participants

Reaction Steps

4-(3-Butenyloxy)benzonitrile (37 g, 0.21 mol; from step (c) above) was mixed with mCPBA (61.6 g, 0.25 mol) and DCM (700 mL) and stirred at r.t for 4 h. The reaction mixture was filtered and 2 mL of DMSO added to destroy the excess mCPBA. The mixture was washed with NaHCO3, then separated, dried and evaporated to give 38.7 g (97%) of the sub-title compound.

Provenance & Evidence