[1-(2-Methoxy-2-methylpropyl)piperidin-4-yl]methylamine → 5-AMINO-6-CHLORO-2-ETHYL-N-{[1-(2-METHOXY-2-METHYLPROPYL)PIPERIDIN-4-YL]METHYL}IMIDAZO[1,2-a]PYRIDINE-8-CARBOXAMIDE

HRID 1743821Notes

Reaction equation

HRID 1743821 reaction equation
[NH2:1][C:2]1[N:7]2[CH:8]=[C:9]([CH2:11][CH3:12])[N:10]=[C:6]2[C:5]([C:13]([OH:15])=O)=[CH:4][C:3]=1[Cl:16].[CH3:17][O:18][C:19]([CH3:30])([CH3:29])[CH2:20][N:21]1[CH2:26][CH2:25][CH:24]([CH2:27][NH2:28])[CH2:23][CH2:22]1>>[NH2:1][C:2]1[N:7]2[CH:8]=[C:9]([CH2:11][CH3:12])[N:10]=[C:6]2[C:5]([C:13]([NH:28][CH2:27][CH:24]2[CH2:23][CH2:22][N:21]([CH2:20][C:19]([O:18][CH3:17])([CH3:29])[CH3:30])[CH2:26][CH2:25]2)=[O:15])=[CH:4][C:3]=1[Cl:16]

Participants

3

Reactant 2

HCID 22236492[1-(2-Methoxy-2-methylpropyl)piperidin-4-yl]methylamineHCID 222364965-Amino-6-chloro-2-ethylimidazo[1,2-a]pyridine-8-carboxylic acid

Product 1

HCID 98235445-AMINO-6-CHLORO-2-ETHYL-N-{[1-(2-METHOXY-2-METHYLPROPYL)PIPERIDIN-4-YL]METHYL}IMIDAZO[1,2-a]PYRIDINE-8-CARBOXAMIDE

Procedure

The title compound was prepared according to the procedure described in the step 6 in EXAMPLE 1, using 5-amino-6-chloro-2-ethylimidazo[1,2-a]pyridine-8-carboxylic acid (EXAMPLE 3, Step 2) and [1-(2-methoxy-2-methylpropyl)piperidin-4-yl]methylamine (EXAMPLE 4, Step 6).

Sources & evidence

ORD record
ord-438da151dd73414897bb4c81d3ef8459
Source dataset
uspto-grants-2006_03
Patent number
US07012080B2

Reaction notes

Loading…