HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Boc-4-(aminomethyl)piperidine → Tert-butyl 4-({[(5-amino-6-chloro-2-methylimidazo[1,2-a]pyridin-8-yl)carbonyl]amino}methyl)piperidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Boc-4-(aminomethyl)piperidine | HCID 736817 | — |
| Reactant | Methyl 5-amino-6-chloro-2-methylimidazo[1,2-a]pyridine-8-carboxylic acid | HCID 67550158 | — |
| Product | Tert-butyl 4-({[(5-amino-6-chloro-2-methylimidazo[1,2-a]pyridin-8-yl)carbonyl]amino}methyl)piperidine-1-carboxylate | HCID 22236490 | — |
Reaction Steps
The title compound was prepared, according to the procedure described in the step 6 of EXAMPLE 1, from 5-amino-6-chloro-2-methylimidazo[1,2-a]pyridine-8-carboxylic acid (EXAMPLE 1, Step 5) and tert-butyl 4-(aminomethyl)piperidine-1-carboxylate (J. Prugh, L. A. Birchenough and M. S. Egbertson, Synth. Commun., 1992, 22, 2357–60).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07012080B2 |
| Source dataset | uspto-grants-2006_03 |
| ORD ID | ord-185bc7c765d44b8894f0dd30b46b4d31 |
| Source note | uspto-grants-2006_03 |