Methyl cyanoacetate → HCID 9900601, compound

HRID 1743885Notes

Reaction equation

HRID 1743885 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:10]=[C:11]([O:14][CH3:15])[C:12]=1[OH:13])[CH:6]=[CH:7][CH:8]=O.[C:16]([CH2:18][C:19]([O:21][CH3:22])=[O:20])#[N:17]>>[C:19](/[C:18](=[CH:8]/[CH:7]=[CH:6]/[C:5]1[CH:4]=[C:3]([O:2][CH3:1])[C:12]([OH:13])=[C:11]([O:14][CH3:15])[CH:10]=1)/[C:16]#[N:17])([O:21][CH3:22])=[O:20]

Participants

3

Reactant 2

HCID 7747Methyl cyanoacetateHCID 1192162-Propenal, 3-(4-hydroxy-3,5-dimethoxyphenyl)-

Product 1

HCID 9900601HCID 9900601, compound

Procedure

The compound was prepared as described in Example 3 by adding 3,5-dimethoxy-4-hydroxycinnamaldehyde (0.15 g, 0.72 mmol) to methyl cyanoacetate (0.064 ml, 0.72 mmol). After refluxing for 1 h and recrystallization from ethanol an orange solid was obtained (0.2 g, 90%). The product gave the following analytical data:

Workup

  1. customThe compound was prepared
  2. temperatureAfter refluxing for 1 h
  3. customrecrystallization from ethanol an orange solid
  4. customwas obtained (0.2 g, 90%)
  5. customThe product gave the following analytical data

Sources & evidence

ORD record
ord-2f6c4c3654f144748a69ca917f4ef6d4
Source dataset
uspto-grants-2006_03
Patent number
US07012095B2

Reaction notes

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