HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pentanal → (5R)-12-butyl-5-ethyl-9-fluoro-5-hydroxy-4,5,13,15-tetrahydro-1H,3H-oxepino[3',4':6,7]indolizino[1,2-b]quinoline-3,15-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pentanal | HCID 8063 | — |
| Reactant | (5R)-5-ethyl-9-fluoro-5-hydroxy-4,5,13,15-tetrahydro-1H,3H-oxepino[3',4':6,7]indolizino[1,2-b]quinoline-3,15-dione | HCID 9929755 | — |
| Product | (5R)-12-butyl-5-ethyl-9-fluoro-5-hydroxy-4,5,13,15-tetrahydro-1H,3H-oxepino[3',4':6,7]indolizino[1,2-b]quinoline-3,15-dione | HCID 69478212 | — |
Reaction Steps
The product of Example 2 is treated with valeraldehyde according to a procedure similar to Stage 13e to produce the expected solid (m.p. 235–236° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07012079B1 |
| Source dataset | uspto-grants-2006_03 |
| ORD ID | ord-50b448b410f94f00b61cc42d887a61ca |
| Source note | uspto-grants-2006_03 |