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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1743969Generated: October 30, 2026

Benzenepropanal → (5R)-5-ethyl-9-fluoro-5-hydroxy-12-phenethyl-4,5,13,15-tetrahydro-1H,3H-oxepino[3',4':6,7]indolizino[1,2-b]quinoline-3,15-dione

https://huagongshe.com/reaction/1743969

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzenepropanalHCID 7707—
Reactant(5R)-5-ethyl-9-fluoro-5-hydroxy-4,5,13,15-tetrahydro-1H,3H-oxepino[3',4':6,7]indolizino[1,2-b]quinoline-3,15-dioneHCID 9929755—
Product(5R)-5-ethyl-9-fluoro-5-hydroxy-12-phenethyl-4,5,13,15-tetrahydro-1H,3H-oxepino[3',4':6,7]indolizino[1,2-b]quinoline-3,15-dioneHCID 69591061—

Reaction Steps

The product of Example 2 is treated with 3-phenylpropanal according to a procedure similar to Stage 13e in order to produce the expected solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07012079B1
Source datasetuspto-grants-2006_03
ORD IDord-4a4dfe63fc5b411daa75aa9005215719
Source noteuspto-grants-2006_03