Sodium Azide → HCID 22236947, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 8.01 g of the compound obtained in Step 2 in 200 ml of dimethylformamide(DMF) was added 8.84 g of sodium azide. The resulting mixture was stirred for 18 hours at 140° C. After the reaction was completed, water was added, and the reaction mixture was extracted with ethyl acetate. The organic phase was dried over anhydrous magnesium sulfate and concentrated under reduced pressure, and the residue thus obtained was purified by a silica gel column chromatography using a mixture of ethyl acetate and n-hexane of 1:6 to obtain 6.2 g of the title compound as an oil.

Provenance & Evidence